Sunday Oct 08, 2023
E26 Wes
Kratom and hair loss. Wes tells how he kicked the kava/kratom "little blue devils". Drugs that use CYP3A to break down may be inhibited by kratom consumption, and hence may cause a dangerous overdose condition with some common pharmaceuticals.
RESOURCE OF WEEK
Kratom can affect certain forms of CYP enzymes that are crucial in the metabolization of other compounds such as pharmaceutical drugs. This can cause adverse drug reactions such as serotonin syndrome, various organ toxicity, and even death in some instances. Common examples: Elavil, Endep, Tofranil, Praminil, Anafranil, Celexa, Lexapro, Cipralex, Paxil, Seroxat, Prozac, Sarafem, Effexor, Effexor XR, Desyrel, Oleptro, Serzone, Buspar, Remeron, Zispin, Seroquel, Abilify, Geodon, Latuda, Clozaril, Erythromycin, Clarithromycin, Telithromycin, Rifampin (Rifampicin), and Rifabutin. “Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom.” Clinical Pharmacology and Therapeutics, March 2023. https://doi.org/10.1002/cpt.2891.
KRATOM IN THE HEADLINES
https://kratomsobriety.com/f/kratom-advocate-extremism-fails-to-prevent-ban-in-zachary-la
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